Pressurized Intraperitoneal Aerosol Chemotherapy( PIPAC) is a new method of giving chemotherapy directly to the peritoneal cavity.
What is PIPAC?
PIPAC is a new method of giving chemotherapy to patients with advanced abdominal cancer, in which chemotherapy is given directly into the abdominal cavity.
Usually, the cancer directed therapy is administered intravenously (through the veins) as a drip. But this method of intraperitoneal chemotherapy is given directly into the abdominal cavity in patients who have cancer spread to the peritoneum, the lining of the abdominal cavity and its organs.
This procedure is simpler compared to the other forms of treatment and the patient has to stay in the hospital for 2 days. Further, the side effects of the treatment are also very minimal and the recovery very quick. It has been also observed that this method has been effective even on patients who couldn’t bear through the process of systemic chemotherapy or have stopped responding to the treatment.
Only 1/10th of the dose of systemic chemotherapy is used in this method, and it produces the same effect and results. Since multiple sessions of PIPAC can be given in the intervals of 6 weeks between each, it can be given alongside routine chemotherapy for better results.